Plus what makes an mRNA vaccine different and how there are more doses of the Pfizer vaccine than expected.
The first coronavirus vaccine has already been administered to thousands of Americans, and a second one from Moderna may get approval from the Food and Drug Administration in the next few days. Below we break down all the facts you need to know about the first week of the vaccine roll-out.
Allergic Reactions to Vaccines Are Rare (But Side Effects Are Normal, Too.)
Two health care workers in Alaska developed allergic reactions in the minutes after receiving Pfizer’s COVID-19 vaccine this week. That may sound scary, but reactions to vaccines are normal and happen in vaccines that have been around for decades. They can be as mild as arm soreness and redness around the injection site or more severe, like an allergic reaction. But serious side effects are extremely rare. In Pfizer’s 44,000 person trial of the coronavirus vaccine, a total of 137 people experienced allergic reactions, or about 0.63%.
The FDA weighed the risks and benefits of the vaccine before approving it for use in the United States and found the benefits easily outweigh the known and potential risks. Pfizer’s trial found the vaccine was about 95% effective at preventing COVID-19, and they did not encounter any serious adverse effects.
Experts agree that the proper protections were already in place as the vaccine is being administered. For instance, guidelines require patients to remain in the hospital or medical center for 15 minutes after getting vaccinated in the event of any adverse reactions. That guideline was followed in the two cases in Juneau, Alaska this week, and in the United Kingdom.
What Is mRNA and How Is It Different From Other Vaccines?
Both the Pfizer and Moderna vaccines work in a new way to protect people from contracting COVID-19. Traditionally, most vaccines use a weakened or dead version of a virus to get the body to produce the antibodies needed to fight.
An mRNA vaccine is different, because it uses messenger RNA as a blueprint to instruct the human body on how to create a protein related to COVID-19. That then allows the body to build antibodies to fight the virus. Once injected, the body can begin to recognize that the vaccine is carrying materials it needs to fight and begins building an immune response and creating antibodies. Then the body’s own immune system will be able to recognize and fight off the coronavirus.
FDA Says Extra Vaccine Doses Good To Use
As the first doses of the Pfizer vaccine were administered this week, some medical personnel noticed that the glass vials used to transport the vaccine hold more doses than they expected. Guidelines show that each vial should contain five doses of the vaccine, but after preparation they contained six or even seven doses.
The FDA issued a statement Wednesday saying that it’s okay for medical workers to use the extra doses and that it’s common for vials to be filled beyond the measurement on the bottle. The extra doses are an instance of good news because it means more people can be vaccinated in this first wave of inoculations than previously thought.
Politics
Malcolm Kenyatta makes history after winning primary for Pa. Auditor General
State Rep. Malcolm Kenyatta, who was first elected to the state House in 2018, won the Democratic nomination for Pa. Auditor General and will...
Biden administration bans noncompete clauses for workers
The Federal Trade Commission (FTC) voted on Tuesday to ban noncompete agreements—those pesky clauses that employers often force their workers to...
Philadelphia DA cancels arrest warrant for state Rep. Kevin Boyle on eve of Pa. primary
Philadelphia District Attorney Larry Krasner said a detective had sought the warrant against Boyle, a Democrat whose district includes a section of...
Local News
What do you know about Wawa? 7 fun facts about Pennsylvania’s beloved convenience store
Wawa has 60 years of Pennsylvania roots, and today the commonwealth’s largest private company has more than 1,000 locations along the east coast....
Conjoined twins from Berks County die at age 62
Conjoined twins Lori and George Schappell, who pursued separate careers, interests and relationships during lives that defied medical expectations,...